About the Thrombosis in Cancer Patients Project
The goal of the TCP project is to advance understanding of cancer-related thrombosis through consideration of preanalytical variables. The project reproduced variable blood sample handling conditions experienced in the clinic and assessed their effects on sample integrity. Blood samples exposed to different preanalytical variables including delay to centrifugation, delay to assay, and freeze/thaw cycles were analyzed on markers of coagulation, fibrinolysis, cellular injury, and inflammation.
High quality blood samples, accompanying clinical and biomarker data, and standard Operating Procedures (SOPs) for collection, handling, and analysis from the TCP project are available to researchers for free. Available data include patient demographics, clinical data including 3 & 6 month follow-up examinations, and analysis results. Blood samples are donated by pre-treatment cancer patients and include prostate, kidney, pancreas, colon, lung, head/neck, breast, lymphoma cases.
Samples Available for Research
| Suspected Cancer Type | Total Cases | Confirmed Cancer Diagnosis | Benign Result |
|---|---|---|---|
| Brain | 6 | 0 | 6 |
| Breast | 25 | 24 | 1 |
| Colon | 10 | 9 | 1 |
| Head & Neck | 10 | 9 | 1 |
| Kidney | 28 | 25 | 3 |
| Leukemia | 6 | 6 | 0 |
| Lung | 35 | 29 | 6 |
| Lymphoma | 14 | 14 | 0 |
| Ovarian | 13 | 5 | 8 |
| Pancreatic | 13 | 9 | 4 |
| Prostate | 26 | 26 | 0 |
| Stomach | 5 | 5 | 0 |
| Total | 191 | 161 | 30 |
Please contact michelle.berny-lang@nih.gov to request samples for research use.