The Center for Strategic Scientific Initiatives Office of the Director (CSSI OD) is responsible for providing oversight and coordination of scientific and programmatic activities for its offices and their programs in order to effectively carry out the mission of CSSI. This includes facilitating extensive reviews and approvals from the NCI Scientific Program Leaders, NCI Board of Scientific Advisors, and the National Cancer Advisory Board.
CSSI OD also oversees programmatic management of two grant programs, the NCI's Provocative Questions Initiative and the Innovative Molecular Analysis Technologies (IMAT) Program. Both of these programs function as trans-divisional, highly collaborative efforts that span multiple disciplines in cancer research to most effectively achieve their goals.
In total the CSSI OD office also involves day-to-day operational management of a combined annual budget of ~$ 190M (FY11) and more than 70 scientific and administrative staff members to assure the Center encourages and rewards new ideas and solutions to personalized cancer medicine.