Dr. Lee serves as a Health Sciences Director within the National Cancer Institute’s (NCI) Office of the Director where his chief responsibility is to help direct the NCI’s Center for Strategic Scientific Initiatives (CSSI). In this role, he provides leadership and input in planning, developing, and implementing rapid strategic scientific and technology initiatives that keep the Institute ahead of the scientific curve of potential new exciting areas and discoveries. This may involve direct development and application of advanced technologies, creation of new trans-disciplinary teams, and/or use of available federal funding mechanisms to forge novel partnerships that emphasize innovation and convergence of scientific disciplines.
Since its inception in 2003, the Center has supported more than 2,000 trans-disciplinary projects through programs such as the Innovation Molecular Analysis Technologies (IMAT), NCI Alliance for Nanotechnology in Cancer, The Cancer Genome Atlas (TCGA), Clinical Proteomic Tumor Analysis Consortium (CPTAC), Physical Sciences-Oncology Centers (PS-OC), Provocative Questions (PQ), and Cancer Target Discovery and Development (CTD2) network. These exploratory initiatives focus on the integration of advanced technologies, trans-disciplinary approaches, infrastructures, and standards, to accelerate the creation of publicly available, broadly accessible, multi-dimensional data, knowledge, and tools to empower the entire cancer research continuum for patient benefit. CSSI has also initiated and supported interagency efforts such as the Big Data Scientist Training Enhancement Program (BD-STEP) with the Department of Veterans Affairs and the Analytical Technologies to Objectively Measure Human Performance (ATOM-HP) project with the Department of Defense.
In 2016, Dr. Lee was assigned to Office of the Vice President to serve as the Deputy Director for Cancer Research and Technology for the White House Cancer Moonshot Task Force. A few key efforts he helped coordinate include the Applied Proteogenomics OrganizationaL Learning and Outcomes Network (APOLLO), international collaborations to share molecular characterization datasets, the Blood Profiling Atlas in Cancer pilot, as well as co-chairing an interagency group focused on cancer data and technology policy issues.
Prior to joining the NCI, his research involved elucidating mechanisms of age-related diseases and has co-authored over twenty papers, five book chapters, and one book. He continues research as an adjunct associate professor at Johns Hopkins University, where he also earned his bachelor`s degree in biomedical engineering and Ph.D. in chemical and biomolecular engineering. He also holds an appointment at the Washington D.C. Veterans Affairs Medical Center and collaborates with clinicians on next generation patient-centered outcomes research. Dr. Lee is a member of the Department of Veterans Affairs’ National Research Advisory Council, the National Academies Board on Science, Technology, and Economic Policy’s Innovation Policy Forum, the Foundation for the NIH’s Biomarkers’ Consortium Cancer Steering Committee, the Health and Environmental Sciences Institute’s Board of Trustees, and the editorial board of Convergence Science Physical Oncology journal.