NCI Emerging Technologies Seminar Series
NCI has established a new seminar series to highlight novel technologies being supported through NCI awards that could transform cancer research and clinical care. The seminar occurs at the end of every month on a Tuesday at 2:00pm Eastern Time. Register through the Event Registration Site.
Tuesday, September 26th, 2023, 2-3pm ET
Speaker: Ji-Xin Cheng, Ph.D., Boston University Photonics Center
Title: Bond-selective imaging to unveil hidden signatures in cancers
Dr. Cheng will discuss novel imaging technologies developed in his lab to enable discovery-driven research towards precision diagnosis and treatment of human diseases.
Tuesday, October 24th, 2023, 2-3pm ET
Speaker: Kristen Naegle, Ph.D., University of Virginia
Title: Molecular and computational tools to unerstand tyrosine phosphorylation in cancer
The Naegle lab uses data-driven approaches to predict and experimental approaches to test the regulation and function of tyorsine phosphorylation in complex networks. In this talk, Dr. Naegle will describe novel chemical methods and computational tools developed in her lab to support this work with a focus on their use in cancer research.
Register through the Event Registration Site. For any questions, please contact Kelly Crotty (Kelly.email@example.com). If you are an individual with a disability who needs reasonable accommodations to participate in this event, please contact the organizers at least five business days before the event so that we can discuss your accommodation request.
Tuesday, August 15th, 2023, 2-3pm ET
Speaker: Muneer Hasham, Ph.D., The Jackson Laboratory
Moderator: Carol Bult, Ph.D., The Jackson Laboratory
Using genetically diverse mouse models for basic cancer research
In this seminar, Dr. Hasham described a strategy developed in his lab to produce genetically diverse mouse models to study human xenografts, including difficult-to-xenograft tumors, that could allow us to understand the contribution of genetic diversity in the tumor microenvironment to the development of cancers.
Tuesday, July 18th, 2023, 2 – 3pm ET
Speaker: Itai Yanai, Ph.D., New York University School of Medicine
Moderator: Josh Campbell, Ph.D., Boston University
Mapping cellular plasticity in tumor progression and drug resistance
Dr. Yanai talked about new informatics tools for inferring cell state tumor microenvironment maps by integrating data from single-cell and spatial transcriptomics studies.
Tuesday, June 20th, 2023, 2 – 3pm ET
Speaker: Ralph Weissleder, M.D, Ph.D., Massachusetts General Hospital and Harvard Medical School
Moderator: Minetta Liu, M.D.
Multiplexed EV analysis for early cancer detection
Dr. Weissleder talked about a novel method for single extracellular vesicle analysis which allows multiplexing (MASEV). This has generated new insight into EV biology and clinical applications.
Tuesday, May 23rd, 2023, 2 – 3pm ET
Speaker: Pallavi Tiwari, Ph.D., University of Wisconsin, Madison
Moderator: Rajan Jain, M.D., NYU Langone Health
Artificial Intelligence and Computational Imaging: Opportunities for Precision Medicine
At this seminar, Dr. Tiwari focused on her lab’s recent efforts in developing machine learning techniques to capture insights into the underlying tumor biology as observed across non-invasive imaging, histopathology, and omics data. She focused on applications of this work for predicting disease outcome, recurrence, progression and response to therapy specifically in the context of brain tumors. She also discussed current efforts in developing new image-based features for post-treatment evaluation and predicting response to chemo-radiation treatment. Dr. Tiwari concluded her talk with a discussion of some of the translational aspects of her work from a clinical perspective.
Tuesday, April 18th 2 - 3pm ET
Speaker: Shana Kelley, Ph.D., Northwestern University
Moderator: David Barbie, M.D., Dana-Farber Cancer Institute
Finding rare cells for therapeutic applications
At this seminar, Dr. Kelley presented a rare cell profiling technology that allows ultra high throughput processing and separation of cell mixtures based on protein expression. Rare tumor-reactive immune cells can be isolated from blood and dissociated tumors to enable the development of cell therapies with enhanced potencies.
Advancing Genomic Technologies for Insights into Extrachromosomal Circular DNA (ecDNA) Structures and Function
ecDNA, prevalent in primary cancers, is associated with aggressive tumor phenotype and poor patient outcome. Recent innovation in genomic technologies have been contributed in the understanding of its diversity and roles in promoting oncogenesis. We discussed these developments and how these approaches can be used to study cancer genome structural variation, oncogenic regulation, and intratumoral heterogeneity.
Tuesday, February 21st 2 - 3pm ET
Speaker: David Hanauer, M.D., M.S., University of Michigan
Moderator: Dana Rollison, Ph.D., Moffitt Cancer Center
EMERSE: an easy-to-use, self-service search engine and chart review tool for EHR notes
At this seminar, Dr. Hanauer described EMERSE - the Electronic Medical Record Search Engine. EMERSE is a tool designed to help non-technical researchers access and make sense of free text (unstructured) notes from electronic health records (EHRs). It is fast and powerful and can help with a wide range of clinical research tasks including cohort identification, eligibility determination, data abstraction, and more.
Wednesday, January 25th 2 - 3pm ET
Speaker: Ning (Jenny) Jiang, Ph.D., University of Pennsylvania
Moderator: Michelle Krogsgaard, Ph.D., NYU School of Medicine
High-throughput and High-dimensional Single T cell Profiling
At this seminar, Dr. Jiang discussed a newly developed technology on linking T cell antigen specificity to TCR sequences, gene expression, and phenotyping at a single cell level and in a high-throughput manner.
Thursday, November 17th 12 - 1pm ET
Speaker: Zeynep Gümüş, Ph.D., Icahn School of Medicine at Mt. Sinai
Moderator: Rachel Karchin, Ph.D., Johns Hopkins University
Development of a Visualization Approach to Enhance Cancer Moonshot Data
This was a joint seminar with the Cancer Moonshot Seminar Series and the DataViz + Cancer program. At this seminar, Dr. Gümüş talked about a user-friendly tool her group is developing to enable researchers of all computational skill levels to visually analyze and explore immune monitoring assay results.
Tuesday, October 18th 2 – 3pm ET
Speaker: Francisco (Paco) Robles, Ph.D., Georgia Institute of Technology and Emory University
Moderator: Milind Rajadhyasksha, Ph.D., Memorial Sloan Kettering Cancer Center
Simple and low-cost optical imaging tools for label-free molecular imaging and 3D microscopy and their application in biomedicine.
At this seminar, Dr. Robles discusses the work his team is leading to advance novel molecular and 3D optical imaging methods to overcome current clinical limitations in biomedicine ranging from hematology to cancer detection.
Tuesday, September 20th 2 – 3pm ET
Speaker: Dino Di Carlo, Ph.D., University of California – Los Angeles
Moderator: Jamie Spangler, Ph.D., Johns Hopkins University
Lab on a particle technology for sorting viable single immune cells based on their function.
At this seminar, Dr. Di Carlo discusses the “lab on a particle” technology being developed in his lab to enable scalable selection of functional immune cells, driving next-generation cancer immunotherapeutic design.
Tuesday, August 23rd 2 – 3pm ET
Speaker: Livia Schiavinato Eberlin, Ph.D., Baylor College of Medicine
Moderator: Anil Sood, M.D., MD Anderson Cancer Center
Placing mass spectrometry in the hands of medical professionals to help guide treatment decisions
At this seminar, Dr. Eberlin discusses a new technology called MasSpec Pen that can assess molecular predictors of disease state from tissue samples. She talks about how this tool can be used clinically for precision medicine-guided surgical resection.
Tuesday, July 26th 2 – 3pm EST
Speaker: Wendell Lim, Ph.D., University of California – San Francisco
Moderator: Antoni Ribas, M.D., Ph.D., University of California – Los Angeles
Rethinking cancer targeting strategies: new synthetic sensors and circuits in the era of smart cell therapeutics
At this seminar, Dr. Lim discusses new methods in cancer -omics and synthetic biology that can lead to nuanced paradigms of tumor recognition. These immuno oncology strategies could more effectively address the complex challenges of treating cancer.